T39A (p.Thr39Ala) variant of TRAF6 (TNF receptor-associated factor 6)
T39A (p.Thr39Ala) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T39A (p.Thr39Ala) variant details
- p.Thr39Ala
- Ensembl rs1859713797
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.17
- MetaLR 0.28
- MetaSVM -0.92
- CADD 3.76
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available