T31I (p.Thr31Ile) variant of TRAF6 (TNF receptor-associated factor 6)
T31I (p.Thr31Ile) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T31I (p.Thr31Ile) variant details
- p.Thr31Ile
- ExAC rs780618300
- TOPMed rs780618300
- gnomAD rs780618300
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.16
- MetaLR 0.35
- MetaSVM -0.84
- CADD 9.82
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the South Asian population (allele frequency 0.00062)
- Structural context available