S41N (p.Ser41Asn) variant of TRAF6 (TNF receptor-associated factor 6)
S41N (p.Ser41Asn) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S41N (p.Ser41Asn) variant details
- p.Ser41Asn
- ExAC rs779230479
- gnomAD rs779230479
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.23
- MetaLR 0.28
- MetaSVM -0.89
- CADD 19.10
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available