S28R (p.Ser28Arg) variant of TRAF6 (TNF receptor-associated factor 6)
S28R (p.Ser28Arg) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S28R (p.Ser28Arg) variant details
- p.Ser28Arg
- ExAC rs765097739
- TOPMed rs765097739
- gnomAD rs765097739
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.31
- MetaLR 0.35
- MetaSVM -0.91
- CADD 0.09
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available