S13R (p.Ser13Arg) variant of TRAF6 (TNF receptor-associated factor 6)
S13R (p.Ser13Arg) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
S13R (p.Ser13Arg) variant details
- p.Ser13Arg
- gnomAD rs1418472079
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.23
- MetaLR 0.35
- MetaSVM -0.47
- CADD 19.50
- PolyPhen-2 0.00
- SIFT 0.45
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available