R99K (p.Arg99Lys) variant of TRAF6 (TNF receptor-associated factor 6)
R99K (p.Arg99Lys) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
R99K (p.Arg99Lys) variant details
- p.Arg99Lys
- TOPMed rs1325843053
- gnomAD rs1325843053
- Missense
- Variant Prioritization Score for Impact Estimate 0.627
- REVEL 0.57
- MetaLR 0.37
- MetaSVM -0.49
- CADD 33.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available