R167G (p.Arg167Gly) variant of TRAF6 (TNF receptor-associated factor 6)
R167G (p.Arg167Gly) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
R167G (p.Arg167Gly) variant details
- p.Arg167Gly
- gnomAD 11-36497215-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.08
- MetaLR 0.03
- MetaSVM -1.03
- CADD 15.80
- PolyPhen-2 0.00
- SIFT 0.62
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available