R167C (p.Arg167Cys) variant of TRAF6 (TNF receptor-associated factor 6)
R167C (p.Arg167Cys) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
R167C (p.Arg167Cys) variant details
- p.Arg167Cys
- ESP rs374431321
- ExAC rs374431321
- TOPMed rs374431321
- gnomAD rs374431321
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.05
- MetaLR 0.05
- MetaSVM -1.04
- CADD 22.70
- PolyPhen-2 0.51
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available