Q166R (p.Gln166Arg) variant of TRAF6 (TNF receptor-associated factor 6)
Q166R (p.Gln166Arg) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
Q166R (p.Gln166Arg) variant details
- p.Gln166Arg
- TOPMed rs1429532893
- gnomAD rs1429532893
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.09
- MetaLR 0.08
- MetaSVM -1.08
- CADD 19.90
- PolyPhen-2 0.14
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available