Q152K (p.Gln152Lys) variant of TRAF6 (TNF receptor-associated factor 6)
Q152K (p.Gln152Lys) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
Q152K (p.Gln152Lys) variant details
- p.Gln152Lys
- ExAC rs763790387
- gnomAD rs763790387
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.11
- MetaLR 0.05
- MetaSVM -1.02
- CADD 17.60
- PolyPhen-2 0.02
- SIFT 0.94
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available