Q152E (p.Gln152Glu) variant of TRAF6 (TNF receptor-associated factor 6)
Q152E (p.Gln152Glu) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
Q152E (p.Gln152Glu) variant details
- p.Gln152Glu
- ExAC rs763790387
- gnomAD rs763790387
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.09
- MetaLR 0.03
- MetaSVM -1.03
- CADD 16.00
- PolyPhen-2 0.18
- SIFT 1.00
- Most common in the Ashkenazi Jewish population (allele frequency 3.9e-05)
- Structural context available