Q116K (p.Gln116Lys) variant of TRAF6 (TNF receptor-associated factor 6)
Q116K (p.Gln116Lys) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
Q116K (p.Gln116Lys) variant details
- p.Gln116Lys
- ExAC rs771304757
- TOPMed rs771304757
- gnomAD rs771304757
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.43
- MetaLR 0.36
- MetaSVM -0.59
- CADD 24.10
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available