P84L (p.Pro84Leu) variant of TRAF6 (TNF receptor-associated factor 6)
P84L (p.Pro84Leu) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
P84L (p.Pro84Leu) variant details
- p.Pro84Leu
- Ensembl rs1564968169
- Missense
- Variant Prioritization Score for Impact Estimate 0.711
- REVEL 0.69
- MetaLR 0.67
- MetaSVM 0.37
- CADD 25.40
- PolyPhen-2 0.66
- SIFT 0.06
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available