P163S (p.Pro163Ser) variant of TRAF6 (TNF receptor-associated factor 6)
P163S (p.Pro163Ser) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
P163S (p.Pro163Ser) variant details
- p.Pro163Ser
- Ensembl rs1564966938
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.09
- MetaLR 0.09
- MetaSVM -1.07
- CADD 17.60
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available