N115Y (p.Asn115Tyr) variant of TRAF6 (TNF receptor-associated factor 6)
N115Y (p.Asn115Tyr) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
N115Y (p.Asn115Tyr) variant details
- p.Asn115Tyr
- Ensembl rs1859671847
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.49
- MetaLR 0.50
- MetaSVM 0.09
- CADD 24.10
- PolyPhen-2 0.34
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available