N109H (p.Asn109His) variant of TRAF6 (TNF receptor-associated factor 6)
N109H (p.Asn109His) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
N109H (p.Asn109His) variant details
- p.Asn109His
- cosmic curated COSV61923
- Missense
- Variant Prioritization Score for Impact Estimate 0.636
- REVEL 0.65
- MetaLR 0.61
- MetaSVM 0.25
- CADD 25.80
- PolyPhen-2 0.94
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 3.1e-05)
- Structural context available