M131V (p.Met131Val) variant of TRAF6 (TNF receptor-associated factor 6)
M131V (p.Met131Val) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
M131V (p.Met131Val) variant details
- p.Met131Val
- ExAC rs758390119
- gnomAD rs758390119
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.09
- MetaLR 0.04
- MetaSVM -1.06
- CADD 20.40
- PolyPhen-2 0.00
- SIFT 0.73
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available