K32E (p.Lys32Glu) variant of TRAF6 (TNF receptor-associated factor 6)
K32E (p.Lys32Glu) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
K32E (p.Lys32Glu) variant details
- p.Lys32Glu
- gnomAD rs1421138534
- Missense
- Variant Prioritization Score for Impact Estimate 0.488
- REVEL 0.41
- MetaLR 0.51
- MetaSVM -0.16
- CADD 23.00
- PolyPhen-2 0.72
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available