I98V (p.Ile98Val) variant of TRAF6 (TNF receptor-associated factor 6)
I98V (p.Ile98Val) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
I98V (p.Ile98Val) variant details
- p.Ile98Val
- TOPMed rs1859711039
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.32
- MetaLR 0.41
- MetaSVM -0.40
- CADD 23.30
- PolyPhen-2 0.04
- SIFT 0.13
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available