I95L (p.Ile95Leu) variant of TRAF6 (TNF receptor-associated factor 6)
I95L (p.Ile95Leu) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
I95L (p.Ile95Leu) variant details
- p.Ile95Leu
- ExAC rs34320471
- TOPMed rs34320471
- gnomAD rs34320471
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.21
- MetaLR 0.21
- MetaSVM -0.95
- CADD 19.10
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 8.4e-05)
- Structural context available