H173R (p.His173Arg) variant of TRAF6 (TNF receptor-associated factor 6)
H173R (p.His173Arg) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
H173R (p.His173Arg) variant details
- p.His173Arg
- gnomAD rs1394703667
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.16
- MetaLR 0.04
- MetaSVM -1.00
- CADD 8.64
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available