H141Q (p.His141Gln) variant of TRAF6 (TNF receptor-associated factor 6)
H141Q (p.His141Gln) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
H141Q (p.His141Gln) variant details
- p.His141Gln
- TOPMed rs1448050815
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -0.97
- CADD 12.00
- PolyPhen-2 0.00
- SIFT 0.79
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available