G11V (p.Gly11Val) variant of TRAF6 (TNF receptor-associated factor 6)
G11V (p.Gly11Val) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
G11V (p.Gly11Val) variant details
- p.Gly11Val
- 1000Genomes rs547082469
- ExAC rs547082469
- gnomAD rs547082469
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.21
- MetaLR 0.42
- MetaSVM -0.50
- CADD 20.80
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the 1KG:PEL population (allele frequency 0.0059)
- Structural context available