E79D (p.Glu79Asp) variant of TRAF6 (TNF receptor-associated factor 6)
E79D (p.Glu79Asp) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
E79D (p.Glu79Asp) variant details
- p.Glu79Asp
- Ensembl rs1859711893
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.25
- MetaLR 0.24
- MetaSVM -0.84
- CADD 17.20
- PolyPhen-2 0.01
- SIFT 0.28
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available