E51G (p.Glu51Gly) variant of TRAF6 (TNF receptor-associated factor 6)
E51G (p.Glu51Gly) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
E51G (p.Glu51Gly) variant details
- p.Glu51Gly
- Ensembl rs1590642478
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.36
- MetaLR 0.46
- MetaSVM -0.21
- CADD 24.20
- PolyPhen-2 0.06
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available