D34G (p.Asp34Gly) variant of TRAF6 (TNF receptor-associated factor 6)
D34G (p.Asp34Gly) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
D34G (p.Asp34Gly) variant details
- p.Asp34Gly
- TOPMed rs1859714097
- gnomAD rs1859714097
- Missense
- Variant Prioritization Score for Impact Estimate 0.495
- REVEL 0.44
- MetaLR 0.49
- MetaSVM 0.02
- CADD 22.40
- PolyPhen-2 0.27
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available