D33G (p.Asp33Gly) variant of TRAF6 (TNF receptor-associated factor 6)
D33G (p.Asp33Gly) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
D33G (p.Asp33Gly) variant details
- p.Asp33Gly
- TOPMed rs76605445
- gnomAD rs76605445
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.26
- MetaLR 0.45
- MetaSVM -0.23
- CADD 23.70
- SIFT 0.23
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available