D18N (p.Asp18Asn) variant of TRAF6 (TNF receptor-associated factor 6)
D18N (p.Asp18Asn) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
D18N (p.Asp18Asn) variant details
- p.Asp18Asn
- gnomAD rs1859715084
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.30
- MetaLR 0.37
- MetaSVM -0.34
- CADD 19.70
- PolyPhen-2 0.20
- SIFT 0.50
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available