D18H (p.Asp18His) variant of TRAF6 (TNF receptor-associated factor 6)
D18H (p.Asp18His) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
D18H (p.Asp18His) variant details
- p.Asp18His
- gnomAD rs1859715084
- Missense
- Variant Prioritization Score for Impact Estimate 0.41
- REVEL 0.26
- MetaLR 0.57
- MetaSVM 0.12
- CADD 23.10
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available