D18G (p.Asp18Gly) variant of TRAF6 (TNF receptor-associated factor 6)
D18G (p.Asp18Gly) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D18G (p.Asp18Gly) variant details
- p.Asp18Gly
- gnomAD rs1859715043
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.18
- MetaLR 0.23
- MetaSVM -0.83
- CADD 21.40
- SIFT 0.59
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available