D150G (p.Asp150Gly) variant of TRAF6 (TNF receptor-associated factor 6)
D150G (p.Asp150Gly) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
D150G (p.Asp150Gly) variant details
- p.Asp150Gly
- gnomAD 11-36497265-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.07
- CADD 23.20
- PolyPhen-2 0.03
- SIFT 0.14
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available