D100N (p.Asp100Asn) variant of TRAF6 (TNF receptor-associated factor 6)
D100N (p.Asp100Asn) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
D100N (p.Asp100Asn) variant details
- p.Asp100Asn
- Ensembl rs1859672400
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.38
- MetaLR 0.28
- MetaSVM -0.70
- CADD 25.40
- PolyPhen-2 0.03
- SIFT 0.07
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available