C90F (p.Cys90Phe) variant of TRAF6 (TNF receptor-associated factor 6)
C90F (p.Cys90Phe) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.90 / 1. The record also includes population frequency data and structural context.
C90F (p.Cys90Phe) variant details
- p.Cys90Phe
- cosmic curated COSV10077
- Missense
- Variant Prioritization Score for Impact Estimate 0.903
- REVEL 0.95
- MetaLR 0.98
- MetaSVM 1.05
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available