C165A (p.Cys165Ala) variant of TRAF6 (TNF receptor-associated factor 6)
C165A (p.Cys165Ala) in TRAF6 (TNF receptor-associated factor 6) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
C165A (p.Cys165Ala) variant details
- p.Cys165Ala
- gnomAD 11-36497220-CA-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.693
- CADD 28.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available