A80V (p.Ala80Val) variant of TRAF6 (TNF receptor-associated factor 6)
A80V (p.Ala80Val) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
A80V (p.Ala80Val) variant details
- p.Ala80Val
- cosmic curated COSV61923
- Missense
- Variant Prioritization Score for Impact Estimate 0.7
- REVEL 0.67
- MetaLR 0.64
- MetaSVM 0.34
- CADD 26.00
- PolyPhen-2 0.66
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available