A29T (p.Ala29Thr) variant of TRAF6 (TNF receptor-associated factor 6)
A29T (p.Ala29Thr) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A29T (p.Ala29Thr) variant details
- p.Ala29Thr
- ESP rs370057355
- ExAC rs370057355
- TOPMed rs370057355
- gnomAD rs370057355
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.11
- MetaLR 0.25
- MetaSVM -0.89
- CADD 4.87
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the South Asian population (allele frequency 0.00017)
- Structural context available