A29P (p.Ala29Pro) variant of TRAF6 (TNF receptor-associated factor 6)
A29P (p.Ala29Pro) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A29P (p.Ala29Pro) variant details
- p.Ala29Pro
- ESP rs370057355
- ExAC rs370057355
- TOPMed rs370057355
- gnomAD rs370057355
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.26
- MetaLR 0.35
- MetaSVM -0.68
- CADD 7.03
- PolyPhen-2 0.15
- SIFT 0.12
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available