A158V (p.Ala158Val) variant of TRAF6 (TNF receptor-associated factor 6)
A158V (p.Ala158Val) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
A158V (p.Ala158Val) variant details
- p.Ala158Val
- gnomAD rs1293716205
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.13
- MetaLR 0.09
- MetaSVM -1.08
- CADD 22.80
- PolyPhen-2 0.01
- SIFT 0.26
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available