A101S (p.Ala101Ser) variant of TRAF6 (TNF receptor-associated factor 6)
A101S (p.Ala101Ser) in TRAF6 (TNF receptor-associated factor 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
A101S (p.Ala101Ser) variant details
- p.Ala101Ser
- gnomAD rs1169399583
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.35
- MetaLR 0.22
- MetaSVM -0.78
- CADD 21.00
- PolyPhen-2 0.12
- SIFT 0.28
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available