Y459H (p.Tyr459His) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
Y459H (p.Tyr459His) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
Y459H (p.Tyr459His) variant details
- p.Tyr459His
- gnomAD 6-111567635-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.28
- CADD 28.50
- PolyPhen-2 0.95
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available