V424M (p.Val424Met) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
V424M (p.Val424Met) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
V424M (p.Val424Met) variant details
- p.Val424Met
- gnomAD 6-111572930-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.34
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available