V412M (p.Val412Met) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
V412M (p.Val412Met) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
V412M (p.Val412Met) variant details
- p.Val412Met
- gnomAD 6-111572942-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.28
- CADD 23.40
- PolyPhen-2 0.97
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available