V412L (p.Val412Leu) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
V412L (p.Val412Leu) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
V412L (p.Val412Leu) variant details
- p.Val412Leu
- rs200053958
- gnomAD 6-111572939-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.07
- CADD 17.40
- PolyPhen-2 0.07
- SIFT 0.43
- Population evidence available
- Structural context available
- Literature evidence available