V412A (p.Val412Ala) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
V412A (p.Val412Ala) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
V412A (p.Val412Ala) variant details
- p.Val412Ala
- gnomAD 6-111572977-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.44
- CADD 27.60
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available