T464A (p.Thr464Ala) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
T464A (p.Thr464Ala) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
T464A (p.Thr464Ala) variant details
- p.Thr464Ala
- rs1562419961
- gnomAD 6-111566557-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.16
- CADD 24.50
- PolyPhen-2 0.92
- SIFT 0.08
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available