R448C (p.Arg448Cys) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
R448C (p.Arg448Cys) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
R448C (p.Arg448Cys) variant details
- p.Arg448Cys
- rs200246882
- gnomAD 6-111567638-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.504
- REVEL 0.28
- CADD 29.90
- PolyPhen-2 0.95
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available