R446Q (p.Arg446Gln) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
R446Q (p.Arg446Gln) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
R446Q (p.Arg446Gln) variant details
- p.Arg446Gln
- rs978486734
- gnomAD 6-111567667-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.21
- CADD 25.00
- PolyPhen-2 0.70
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available