L460F (p.Leu460Phe) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
L460F (p.Leu460Phe) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
L460F (p.Leu460Phe) variant details
- p.Leu460Phe
- gnomAD 6-111567632-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.532
- REVEL 0.34
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available