K463R (p.Lys463Arg) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
K463R (p.Lys463Arg) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
K463R (p.Lys463Arg) variant details
- p.Lys463Arg
- gnomAD 6-111566520-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.25
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available