K454E (p.Lys454Glu) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
K454E (p.Lys454Glu) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
K454E (p.Lys454Glu) variant details
- p.Lys454Glu
- gnomAD 6-111567650-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.12
- CADD 24.00
- PolyPhen-2 0.25
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available